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J.A. Jeevendra Martyn, M.D.

J.A. Jeevendra Martyn, M.D.

J.A. Jeevendra Martyn, M.D., FRCA, FCCM, is the chief of anesthesiology at Shriners Hospitals for Children — Boston. He is also a professor at Harvard Medical School and the director of the Clinical and Biochemical Pharmacology Lab at Massachusetts General Hospital and Shriners Hospitals for Children — Boston.

As anesthetist-in-chief, Dr. Martyn oversees his research on neuromuscular physiology and pharmacology, with specific focus on myopathy of critical illness; critical care physiology and pharmacology related to trauma, sepsis and burns, with special emphasis on adrenoceptor and growth factor signaling; and clinical pharmacology and neurobiology of pain, as well as pediatric anesthetic pharmacology.

Dr. Martyn’s research work ranges from cell culture, whole-animal/human studies and pharmacokinetics to molecular medicine. His investigations in humans led to the use of thermodilution as a measure of cardio dynamics. His studies on the clinical and basic pharmacology of a number of important drugs, such as neuromuscular blocking agents, adrenoceptor agonists, sedative and narcotic drugs, and H2-receptor antagonists, have explained the mechanisms that account for the altered responses to these drugs in critically ill and burned patients. These studies have ultimately redefined the dosing schedules for several drugs commonly used in the burn intensive care unit. His seminal studies described insulin signaling aberrations that lead to insulin resistance in burns and other muscle wasting conditions. Currently his work focuses on the role of burn-induced spinal cord changes that lead to muscle wasting, and the cause of increased opiate requirement in burns and methods to alleviate the tolerance to opiates in burned subjects.

Dr. Martyn has over 200 journal articles in top tier journals, as well as many books and chapters. Extra-mural grants have been awarded to Dr. Martyn for over 30 years: National Institute of Health/NIGMS P-50; R01 grants; SHC — Research Philanthropy grants.

Dr. Martyn has received numerous awards and honors including:

  • Supervisor and mentor for many first prize winners of Resident Research Contest Award at the American Society of Anesthesiology and American Burn Association
  • Nobel Prize Nominating Committee for Physiology and Medicine, 1993–present
  • Excellence in Research Award from the American Society of Anesthesiology

Current positions:

  • Anesthetist-in-Chief, Shriners Hospitals for Children — Boston
  • Professor, Harvard Medical School
  • Director, Clinical and Biochemical Pharmacology Lab., Massachusetts General Hospital and Shriners Hospitals for Children — Boston

Education/training:

  • MBBS, University of Ceylon, Colombo, Sri Lanka
  • FRCA, Fellow, Royal College of Anaesthetists, England
  • FACA, Diplomate, American Board of Anesthesiology
  • MA, Honoris Causa, Harvard University, Boston, Mass.
  • Residency in Anesthesiology, Columbia Presbyterian Hospital, New York, N.Y.
  • Clinical Fellow in Anesthesia, College of Physicians and Surgeons, Columbia University, New York, N.Y.
  • Chief Resident in Anesthesia, Columbia University, Presbyterian Hospital, New York
  • Registrar, Nuffield Department of Anaesthetics, Radcliffe Infirmary, University of Oxford, England
  • NIH Postdoctoral Research Fellow in Anaesthesia and Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Mass.

Scholarly activities:

NCBI list of publications